Why Tamoxifen?

Tamoxifen blocks the actions of the hormone estrogen. Certain types of breast cancer require estrogen to grow.

Most important fact about Tamoxifen?

Treatment with tamoxifen may increase the risk of certain uterine cancers, stroke, and pulmonary embolism (blood clot in the lung), which may be fatal. You should discuss with your doctor the risks and benefits associated with the use of tamoxifen.

How should you take Tamoxifen?

Tamoxifen can be taken with or without food.It is important to take tamoxifen regularly to get the most benefit.

What side effects may occur?

Stop taking tamoxifen and seek emergency medical attention or contact your doctor immediately if you experience any of the following serious side effects: * an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives); * possible symptoms of a stroke such as unusual weakness, drowsiness, confusion, or difficulty walking or talking; * possible symptoms of a blood clot in the lung such as chest pain, shortness of breath, or coughing up blood; * possible symptoms of a blood clot in the brain or leg such as blurred vision, changes in vision, numbness, or pain or swelling in a leg; * new breast lumps; * bone pain; * menstrual changes, abnormal vaginal bleeding, vaginal discharge, or pelvic pain or pressure; * pain or tenderness in the upper abdomen; * yellowing of the skin or eyes; or * excessive nausea, vomiting, or thirst.

Why should Tamoxifen not be prescribed?

Before taking tamoxifen, tell your doctor if you * have a history of deep vein thrombosis (blood clot in the leg); * have a history of pulmonary thrombosis (blood clot in the lung); or * take the blood thinner warfarin (Coumadin).